fa نانوذرات طلا بر پایه عصاره رازیانه: بیوسنتز و خصوصیات <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">سابقه و اهداف:</span></span></span></b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"> دانه های رازیانه </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">F. vulgare</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"> سرشار از متابولیت های مختلف ثانویه گیاهان (فیتوشیمیایی) مانند: اسیدهای پلی فنلی، فلانوئیدها و ساپونین ها هستند</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">. </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">روش بررسی:</span></span></span></b><b> </b><a name="_Hlk90815944"><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">پس ازعصاره&shy;گیری دانه رازیانه با استفاده از شوف بالن، </span></span></span></a><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">عصاره حاصل حاوی آنتول صاف گردیده، در بالن ژوژه ته گرد به محلول 5/0گرم نمک طلا در 250 میلی لیتر آب دیونیزه با حرارت نقطه جوش اضافه گردید.</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">یافته ها:</span></span></span></b> <span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">رسوب سیاه رنگی از محلول نانوذره به رنگ قرمز یاقوتی بدست آمد. </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">آزمون&shy;های</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">SEM</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">, </span></span>&nbsp;<span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">TEM</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">,</span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"> اندازه نانوذرات کمتر از 20 نانومتر بدست آمد. </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">FT-IR</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"> وجود ذرات فلز را اثبات نمود. نمایش پراکندگی نانوذرات طلا با </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">استفاده از </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">map</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">analysis</span></span></span> <span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">عناصر تشکیل دهنده</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"> با استفاده از </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">EDX</span></span></span><span style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"> به طور مناسبی ت</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">أ</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">یید شدند.</span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">نتیجه گیری:</span></span></span></b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:"> نتایج بررسی تست های تاییدی </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">FT-IR</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">, </span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">SEM</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">, </span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">TEM</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">, </span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">EDX</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">, </span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">map</span></span></span> <span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">analysis</span></span></span> <span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" nazanin="" style="font-family:">&nbsp;حاکی از تایید اندازه و شکل نانوذرات سنتز شده در این تحقیق می باشد. با بررسی اثر آن بر روی سلول های سرطانی، می توان کیفیت و میزان کشندگی آنها را نیز بررسی نمود.</span></span></span></span></span></span></span></span><br> &nbsp; <span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span dir="RTL" new="" roman="" style="font-family:" times="">‌</span></b><b><span new="" roman="" style="font-family:" times="">Background & objectives:</span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> F. vulgare fennel seeds are rich in various secondary (phytochemical) plant metabolites such as polyphenolic acids, flavonoids and saponins.</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Materials </span></span></b><b><span style="background:white"><span new="" roman="" style="font-family:" times=""><span style="color:black">&</span></span></span></b><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> methods:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> After extracting fennel seeds using a balloon shuffle, the resulting extract containing anethole was filtered. In a round bottom flask, 0.5 g of gold salt was added to 250 ml of deionized water at boiling point. </span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Results</span></span></b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">: Black precipitate was obtained from ruby ​​nanoparticle solution. SEM, TEM and nanoparticle sizes less than 20 nm were obtained. FTIR proved the presence of metal particles. The scattering of gold nanoparticles using map analysis of the constituent elements using EDX was appropriately confirmed. </span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Conclusion</span></span></b><span lang="EN" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">: The results of FTIR, SEM, TEM, EDX and map analysis confirmation tests confirm the size and shape of nanoparticles synthesized in this study. By examining its effect on cancer cells, we can also evaluate their quality and mortality. </span></span></span></span></span></span><br> &nbsp; نانوذرات طلا, رازیانه, آنتول. Gold nanoparticles, fennel, anethole 0 0 http://tmuj.iautmu.ac.ir/browse.php?a_code=A-10-1-652&slc_lang=fa&sid=1 Hanieh Voshmgiri حانیه وشمگیری 100319475328460010728 100319475328460010728 No Department of Biochemistry and Biophysics, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran گروه بیوشیمی و بیوفیزیک، دانشکده علوم و فناوری های نوین، واحد علوم پزشکی تهران، دانشگاه آزاد اسلامی، تهران، ، ایران Fereshteh Atabi فرشته عتابی f.atabi@iautmu.ac.ir 100319475328460010729 100319475328460010729 Yes Department of Biochemistry and Biophysics, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran 1. گروه بیوشیمی و بیوفیزیک، دانشکده علوم و فناوری های نوین، واحد علوم پزشکی تهران، دانشگاه آزاد اسلامی، تهران، ، ایران Malihe Entezari ملیحه انتظاری 100319475328460010730 100319475328460010730 No Department of Genetics, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. گروه ژنتیک، دانشکده علوم و فناوری های نوین، واحد علوم پزشکی تهران، دانشگاه آزاد اسلامی، تهران، ، ایران Malak Hekmati ملک حکمتی 100319475328460010731 100319475328460010731 No Department of Organic Chemistry, Faculty of Pharmaceutical Chemistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran گروه شیمی آلی، دانشکده شیمی دارویی، علوم پزشکی تهران، دانشگاه آزاد اسلامی، تهران، ، ایران