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:: Volume 34, Issue 2 (summer 2024) ::
MEDICAL SCIENCES 2024, 34(2): 105-111 Back to browse issues page
The use of artificial intelligence (AI) in pharmacology and the process of drug discovery
Pouyan Pishva1
1- Department of Pharmacology and Toxicology, Faculty of Pharmacy and Pharmaceutical Sciences, Tehran Medical Sciences, Islamic Azad University (IAUPS), Tehran, Iran
Abstract:   (736 Views)
Background: The invention of artificial intelligence has changed the way of life in general. Currently, artificial intelligence is used throughout the pharmacology research and the field of drug discovery, and this technology has the power to revolutionize the drug discovery process and improve efficiency, accuracy, and time of process.
Materials and methods: In this review article, the results of the published articles were systematically analyzed into the topics of artificial intelligence application in pharmacology, drug industry and drug discovery. The information obtained from the above articles was also classified and reviewed in the same order.
Results: The review of 88 revealed the benefits of using artificial intelligence including the expansion and improvement of structures in the drug design process (such as the drug INS018-055 for the treatment of pulmonary fibrosis), better prediction of the effect of the ligand on the receptor, and better cooperation of the health care providers. Disadvantages were the problems of scientific decision-making with artificial intelligence, ethical concerns in the field of pharmaceuticals and recognition of the limitations of approaches based on artificial intelligence. Strengthening neural networks of databases, integration of artificial intelligence with traditional experimental methods, as well as the use of in silico computer tools facilitate the possibility of solving problems.
Conclusion: The optimal use of artificial intelligence approaches will lead to the acceleration of the drug discovery process, therefore, it is necessary to carry out more studies related to the effect of artificial intelligence in pharmaceutical research.
 
Keywords: Artificial intelligence, Pharmacology, Data analysis, Drug discovery
Full-Text [PDF 316 kb]   (456 Downloads)    
Semi-pilot: Systematic Review | Subject: Pharmacology
Received: 2023/11/19 | Accepted: 2023/12/28 | Published: 2024/06/30
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pishva P. The use of artificial intelligence (AI) in pharmacology and the process of drug discovery. MEDICAL SCIENCES 2024; 34 (2) :105-111
URL: http://tmuj.iautmu.ac.ir/article-1-2172-en.html


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Volume 34, Issue 2 (summer 2024) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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