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:: Volume 26, Issue 3 (fall 2016) ::
MEDICAL SCIENCES 2016, 26(3): 157-165 Back to browse issues page
Effects of olive oil on kidney, lipid and liver function in male rat
Davood Moghadamnia 1, Mokhtar Mokhtari2 , Saeed Khatamsaz3
1- PhD Animal Physiology , Department of Biology, Islamic Azad University, Fars Science and Research Branch, Shiraz, Iran , davood.moghadamnia@gmail.com
2- Department of Biology, Islamic Azad University, Shiraz Branch, Shiraz, Iran
3- Department of Biology, Islamic Azad University, Kazerun Branch, Kazerun, Iran
Abstract:   (10407 Views)

Background: Components of olive oil include oleic acid, hydrocarbons (as squalene), sterols (as beta-sitosterol), polyphenols (tyrosol, hydroxyltyrosol, oleuropeinand, and others), tocopherols and terpenoids. Olive oil ingredients have anti-inflammatory, antioxidant, anti-arrhythmic, anti-inflammatory and vasodilatory effects. The present study was done to evaluate the effects of olive oil on kidney, lipid and liver function in male rat.

Materials and methods: In this experimental study, 14 male rats were divided into 2 groups. In control group, each rat underwent no stress such as injection, oral gavage and etc. in experimental group, each rat received 0.4 mL olive oil orally per day for 3 months. All animals bled after 3 months. The blood samples were tested for creatinine, nitrogen urea blood (BUN), total cholesterol, LDL and HDL cholesterol, triglyceride, sodium, glucose, SGOT, SGPT, ALP, GGT, albumin and  total protein serum levels.

Results: No significant differences were noticed in sodium, BUN, total cholesterol, LDL cholesterol, HDL cholesterol and triglyceride serum levels in rats treated with olive oil compared to control group. There were no significant differences in SGOT, SGPT, ALP, GGT, albumin and total protein serum levels between rats treated with olive oil and control group.

Conclusion: The results showed that olive oil had no effects on kidney, lipid and liver function.

Keywords: Olive oil, Kidney function, Lipid function, Liver function, Glucose, Male rat.

Keywords: Olive oil, Kidney function, Lipid function, Liver function, Glucose, Male rat.
Full-Text [PDF 885 kb]   (2590 Downloads)    
Semi-pilot: Experimental | Subject: Animal Biology
Received: 2016/01/17 | Accepted: 2016/04/4 | Published: 2016/09/17
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Moghadamnia D, Mokhtari M, Khatamsaz S. Effects of olive oil on kidney, lipid and liver function in male rat. MEDICAL SCIENCES 2016; 26 (3) :157-165
URL: http://tmuj.iautmu.ac.ir/article-1-1130-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 26, Issue 3 (fall 2016) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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