Background: Hemorrhoid disease, as the most common digestive disease and the most common cause of lower gastrointestinal bleeding, is the most common in ages of 65-45 years that can disturb quality of life of patients with developing various painful symptoms.

Materials and methods: The cross sectional study was done on patients with hemorrhoids referred to Buali, Resalat and Milad Hospital surgical clinics in Tehran within one year, and candidates for hemorrhoidectomy. For patients in stapled hemorrhoidopexy group (n=40) and hemorrhoidectomy (n=40), questionnaires of SF36, VAS, and MPQ were completed. Significance level was set at 0.05.

 Results: In this study, most participants were male (55%). Quality of life, 6 months after surgery, in those who underwent stapled hemorrhoidectomy was better than another group. The mean pain score in patients with stapled hemorrhoidopexy in 24 hours and 6 months after surgery was significantly lower than in the hemorrhoidectomy group.

Conclusion: Regardi our results and other studies, stapled hemorrhoidopexy is a safe and effective alternative for the treatment of hemorrhoids, with effects on reducing postoperative pain.

Keywords: Hemorrhoidectomy, Hemorrhoidopexy, Stapled, Quality of life, Comparison of pain, Central Tehran hospital.