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Prevalence of adenovirus infection and the dominant serotype among patients with acute gastroenteritis in Tehran between May 2008 and May 2009
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Behzad Damavand1   , Pedram Azimzadeh2 , Seyed Reza Mohebbi 3, Sara Romani4 , Sajjad Majidizadeh Bozorgi1 , Farzaneh Jadali5 , Mohammad Reza Zali6 |
1- Researcher, BS of Microbiology, Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical sciences, Tehran, Iran
2- Researcher, MSc of Cellular and Molecular, Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical sciences, Tehran, Iran
3- PhD of Virology, Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical sciences, Tehran, Iran , srmohebbi@gmail.com
4- Researcher, MSc of Microbiology, Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical sciences, Tehran, Iran
5- Pathologist, Department of pathology and Laboratory Sciences, Mofid Pediatric Hospital, Shahid Beheshti University of Medical sciences, Tehran, Iran
6- Gastroenterologist, Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical sciences, Tehran, Iran |
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Abstract: (12391 Views) |
Background: Adenoviruses are double-stranded DNA and non-enveloped viruses. It causes different diseases in human through respiratory, urinary and gastrointestinal tracts. Interestingly, more than fifty serologic types of human adenovirus were distinguished and just serotypes 40 and 41 cause gastroenteritis in human. The purpose of this study was to evaluate the prevalence of adenovirus infection in patients with acute gastroenteritis in the population of Tehran.
Materials and methods: between May 2008 and May 2009, 293 stool samples were collected from patients with acute gastroenteritis. After DNA extraction, PCR procedures were performed, using designed primers. Positive adenoviruses samples were analyzed by the software and their serotypes were determined.
Results: 6 positive samples of 293 patients recruited to the hospital were children less than 5 years old. Additionally, they were diagnosed as serotype 41 of adenoviruses F group.
Conclusion: According to our results, serotype 41 of adenovirus was an important cause of gastroenteritis in less than 5 years old children in population of Tehran. |
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| Keywords: Adenovirus, Gastroenteritis, Tehran, Serotype 41 |
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Full-Text [PDF 297 kb]
(5611 Downloads)
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Semi-pilot: Survey/Cross Sectional/Descriptive |
Subject:
Microbiology
Received: 2013/03/16 | Accepted: 2013/05/28 | Published: 2013/05/28
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