[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 23, Issue 3 (fall 2013) ::
MEDICAL SCIENCES 2013, 23(3): 196-200 Back to browse issues page
Evaluation of efficiency of some disinfectants in disinfection of water treatment system in the pharmaceutical industry and select the best one
Ramin Asgharian *1, Asal Heidari2, Ali Montaseri2, Assem Abdollahpour3, Saeed Ghiaee4, Maryam Aminian5
1- PhD of Industrial Pharmacy, Islamic Azad University, Pharmaceutical Sciences Branch, Tehran, Iran , ramin3205@gmail.com
2- Pharmacist, Islamic Azad University, Pharmaceutical Sciences Branch, Tehran, Iran
3- PhD of Analytical Chemistry, International Center for Science and High Technology and Environmental Science, Kerman, Iran
4- Pharmacist, Deputy of Control and Research, Jaber ebne Hayyan Pharmaceutical Company, Tehran, Iran
5- MSc of Microbiology, Chief of Microbial Control Laboratory, Jaber ebne Hayyan Pharmaceutical Company, Tehran, Iran
Abstract:   (9319 Views)
Background: Water used in the pharmaceutical industry should have special physicochemical and microbiological characteristics. One of the quality items of pharmaceutical water is level of microbial content. For this reason selection of effective disinfection method is the main item for design of pharmaceutical water systems. Water systems can be maintained at temperature below 10 ºC and more than 70 ºC but maintaining of water at ambient temperature could increase of microbial content. In this condition use of disinfectant is useful for reducing of microbial content. Some of them such as chloride, ozone and hydrogen peroxide due to good results have more application.
Materials and Methods: In this study, effect of three disinfectants chloride, ozone and hydrogen peroxide with 1 ppm concentration, consider on five microorganisms Pseudomonas aeruginosa, Staphylococcus aureus, candida albicans, Aspergillus niger and E.coli.
Results: Counting and decreasing of microorganisms showed the efficiency of disinfectants.
Conclusion: Finally ozone was selected as the best disinfectant due to high efficiency.
Keywords: Pharmaceutical Water, Microbial control, Biofilm, Ozone, Cl2, H2O2
Full-Text [PDF 185 kb]   (1653 Downloads)    
Semi-pilot: Experimental | Subject: Pharmacology
Received: 2013/09/22
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Asgharian R, Heidari A, Montaseri A, Abdollahpour A, Ghiaee S, Aminian M. Evaluation of efficiency of some disinfectants in disinfection of water treatment system in the pharmaceutical industry and select the best one. MEDICAL SCIENCES. 2013; 23 (3) :196-200
URL: http://tmuj.iautmu.ac.ir/article-1-706-en.html


Volume 23, Issue 3 (fall 2013) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 3991