Background: Heart diseases represent the most common causes of mortality worldwide. Knowledge towards heart disease and its risk factors is an important pre-requisite for an individual to implement behavioral change leading towards heart disease prevention. The aim of the present study was to determine the effect of education on knowledge of students' parents' towards cardiovascular risk factors.

Materials and methods: This interventional study was carried out in Tehran 13th district. A well-prepared questionnaire was used to collect initial data. Data analysis was achieved by SPSS software using ANOVA, paired t-test and correlation coefficient.

Results: Totally, 432 subjects with the mean age of 34.6±5.9 years took part in our study, of whom 89.1% were householder. The mean knowledge score was significantly differed before and after education (p<0.05).

Conclusion: Unfortunately, parents' knowledge of cardiovascular risk factors were not adequate. This study suggests that educational programs can positively influence the knowledge towards cardiovascular risk factors.