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:: Volume 32, Issue 2 (summer 2022) ::
MEDICAL SCIENCES 2022, 32(2): 185-195 Back to browse issues page
The relationship between laboratory and chest computed tomography scan findings and severity of COVID-19 cases: a single center study
Mehrangiz Zangeneh1 , Termeh Tarjoman2 , Arian Shahidi3 , Mahnaz Valizadeh4 , Zahra Hanifezadeh5 , Omid Ameli6 , Nazi Saljoughi3 , Behnam Farhoodi1 , Masoumeh Mesgarian 7
1- Department of Infection Disease, Faculty of Medicine, Amir-al-Momenin Hospital Tehran Medical Sciences, Islamic Azad University Tehran, Iran
2- Social Determinants of Health Research Center, Amir-al-Momenin Hospital Tehran Medical Sciences, Islamic Azad University Tehran, Iran
3- MD, Faculty of Medicine, Amir-al-Momenin Hospital Tehran Medical Sciences, Islamic Azad University Tehran, Iran
4- Department of Internal Disease, Faculty of Medicine, Amir-al-Momenin Hospital Tehran Medical Sciences, Islamic Azad University Tehran, Iran
5- Bachelor of Midwifery, Amir-al-Momenin Hospital Tehran Medical Sciences, Islamic Azad University Tehran, Iran
6- Nursing Student, Amir-al-Momenin Hospital Tehran Medical Sciences, Branch, Islamic Azad University Tehran, Iran
7- Department of Infection Disease, Faculty of Medicine, Amir-al-Momenin Hospital Tehran Medical Sciences, Islamic Azad University Tehran, Iran , mmesgarian.ac.ir
Abstract:   (1720 Views)
Background: Para-clinical abnormalities are considered as predictors of COVID-19 severity. We aimed at evaluate the relationship between laboratory and chest computed tomography (CT) scan findings and severity of COVID-19 cases.
Materials and methods: We performed a retrospective study on confirmed COVID-19 patients in Amir-Al-Momenin hospital, Tehran, Iran, from February 20, 2020 to April 19, 2020. Para-clinical characteristics of the patients including chest CT scan and laboratory findings were recruited from patients’ medical records. Then we evaluated the relationship between laboratory and chest CT scan findings and severity of COVID-19 cases. We performed statistical analysis using descriptive methods and analytical tests by SPSS statistical software version-24.
Results: With lung involvement to more than 50%, the severity of the disease changed severely and critically (P=0.008). In addition, WBC and Poly counts, ALP and BUN levels increased with increasing disease severity (P> 0.05). Predictive variables explain 32.4% of the changes in the criterion variable.
Conclusion: Lung involvement more than 75% and poly count variables were positive predictors of disease severity. Indeed, each unit increase in lung involvement ploy count, disease severity increases by 27.1% and 43.8%, respectively. Laboratory and chest CT scan findings can be efficient tools for prognostic stratification of COVID-19 patients and management of this infection.
Keywords: COVID-19, Prognosis, Patient outcome assessment, Tomography, Hematologic tests
Full-Text [PDF 373 kb]   (670 Downloads)    
Semi-pilot: retrospective | Subject: Infectious Diseases
Received: 2021/10/5 | Accepted: 2021/11/10 | Published: 2022/07/1
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Zangeneh M, Tarjoman T, Shahidi A, Valizadeh M, Hanifezadeh Z, Ameli O, et al . The relationship between laboratory and chest computed tomography scan findings and severity of COVID-19 cases: a single center study. MEDICAL SCIENCES 2022; 32 (2) :185-195
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Volume 32, Issue 2 (summer 2022) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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