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The effects of N- acetyl- l- cysteine on reduction of semen viscosity
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Keramatollah Dehghani   1, Farideh Foroughian , Ali Tajik , Parisa Taghavi4 |
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Abstract: (24962 Views) |
Background: Hyperviscous semen is an etiologic cause for male-related infertility which is related to function of oxidative systems in the cells. So, use of anti-oxidants may be useful. Hence, this study was conducted to evaluate the efficacy of N-acetyl-l-cysteine in reduction of seminal viscosity.
Materials and methods: In this experimental study, 200 patients attending to urology clinic of Amiralmomenin hospital with hyperviscouse semen were selected and treated with N-acetyl-l-cysteine, 500 mg twice a day for one month. Sperm analysis was repeated after treatment and 10 days later.
Results: After treatment, the viscosity which was initially high in all patients was normal in 124 men (62%), high in 60 patients (30%), and low in 16 subjects (8%). Also sperm count, motility, and morphology were improved significantly after the treatment (p< 0.05).
Conclusion: According to 70 percent efficacy for Nacetyl-l-cysteine and lack of any drug adverse effects, this therapeutic modality may be indicated upon with patient's conditions and physician's opinion. |
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| Keywords: Viscosity, Semen, N-acetyl-l-cysteine. |
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Full-Text [PDF 421 kb]
(9898 Downloads)
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Subject:
Epidemiology
Received: 2010/09/4 | Published: 2010/09/15
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