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Background: Bernard soulier syndrome (BSS) is a rare congenital bleeding disorder characterized by thrombocytopenia. BSS causes bruising, epistaxis, gingival bleeding, menorrhagia, post partum bleeding, gastrointestinal bleeding and post traumatic hemorrhage, but there is no report of hemoptysis in BSS.
 Case Report: A 14 year-old girl was referred to our center due to massive hemoptysis. Her chest x-ray revealed complete collapse of the right lung. Rigid bronchoscopy was preformed and the intrabronchial clots were removed. Smear and culture of direct sputum was positive for Mycobacterium tuberculosis. She received anti-tuberculosis treatment. During treatment, she developed a massive vaginal bleeding, because of drug interaction between rifampin and low dose contraceptive (LD), which she had been taking for control of massive menstrual bleeding. Her vaginal bleeding was controlled by platelet infusion and recombinant factor 7 infusion. After 2 months of anti-TB treatment, sputum smear and culture for BK converted to negative. One year after treatment, the pulmonary tuberculosis was completely cured and no hemoptysis occurred.
 Conclusion: When hemoptysis occurs in patients with Bernard soulier syndrome, we should consider other differential diagnoses, and further diagnostic evaluation is recommended.

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Background: Cystic fibrosis (CF) is a genetically disease with different respiratory and gastrointestinal organ involvement. Because of gastrointestinal tract involvement, patients have mal-absorption for vitamins and mineral elements for example vitamin A, D, E and trace elements such as Selenium (Se), Zinc (Zn) and Copper (Cu) have low serum level in CF patients in different studies. The goal of this study is to define relation between serum level of this elements and severity of respiratory and gastrointestinal tract involvement in these patients.
Materials and methods: This cross sectional study performed on 39 cystic fibrosis patients admitted in pediatric ward of Masih Daneshvari hospital, Tehran, Iran. Serum levels of Vitamin A, D and E, Selenium, Zinc and Copper deficiency were studied.
 Results: Serum level of Vitamin A and D were lower than normal values. Also, 3 cases (7.68%) had serum level of Zinc lower than normal values.
Conclusion: CF patients are susceptible to have deficiencies of fat soluble vitamins and trace elements such as Selenium and Zinc because of mal-absorption. It seems that a perfect diet and nutritional components are helpful in prevention of these problems.
Keywords: Cystic fibrosis, Zinc, Copper, Selenium, Vitamin.

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Background: Vitamin D deficiency is related to acute myocardial infarction (MI) directly and indirectly. Therefore, this study evaluated serum level of vitamin D in patients with acute MI.
Materials and methods: This is a cross-sectional and descriptive study on 84 patients with acute MI in Amiralmomenin hospital since May 2018 to May 2019. The demographic information of patients including risk factors for MI as: age, gender, body mass index, hypertension, hyperlipidemia, diabetes, cigarettes use or drugs abuse, history of cardiovascular diseases, inpatient time, and vitamin D status are gathered as questionnaires. The data was added to SPSS version 25, and the P-value of 0.05 was considered significant.
Results: 52.4% of patients were female. All the patients were 36 to 90 years old, and the mean (±standard deviation) age was 67.51±12.90 years old. 25% of the patients had vitamin D deficiency, 23.8% insufficiency, 11.9% severe deficiency, and 51.2% normal value. However, none of the risk factors were related to the vitamin D status significantly.
Conclusion: In this study, none of the risk factors were related to vitamin D status in MI patients, yet cohort studies with major samples are required because there are several studies confirm that vitamin D status has an important role in development of acute MI.