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Background: Hyperviscous semen is an etiologic cause for male-related infertility which is related to function of oxidative systems in the cells. So, use of anti-oxidants may be useful. Hence, this study was conducted to evaluate the efficacy of N-acetyl-l-cysteine in reduction of seminal viscosity.
Materials and methods: In this experimental study, 200 patients attending to urology clinic of Amiralmomenin hospital with hyperviscouse semen were selected and treated with N-acetyl-l-cysteine, 500 mg twice a day for one month. Sperm analysis was repeated after treatment and 10 days later.
Results: After treatment, the viscosity which was initially high in all patients was normal in 124 men (62%), high in 60 patients (30%), and low in 16 subjects (8%). Also sperm count, motility, and morphology were improved significantly after the treatment (p< 0.05).
 Conclusion: According to 70 percent efficacy for Nacetyl-l-cysteine and lack of any drug adverse effects, this therapeutic modality may be indicated upon with patient's conditions and physician's opinion.

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Background: Various surgical procedures have been developed to repair stress urinary incontinence in women. This study aims to compare the efficacy of two common methods open Burch colposuspension and transvaginal tape.
Materials and methods: In this experimental study, 283 married women with stress urinary incontinence was undergone either open Burch colposuspension (157 patients) or transvaginal tape (126 patients) surgical procedures between 1993 and 2011. Outcomes of surgical procedures were evaluated 6 and 12 months after surgery. A concurrent cystocele existed in 262 women that were repaired simultaneously during Burch colposuspension (157 patients) or transvaginal tape (105 patients) procedures.
Results: The success rates in Burch group were higher than transvaginal tape group at the 6th month (99.4% vs. 94.4%) and the 12th month (97.5% vs. 50%) (p<0.05). Repair of concurrent cystocele was successful in all patients of the Burch group and 93.3% of patients of the transvaginal tape group.
Conclusion: We recommend open Burch colposuspension to repair stress urinary incontinence in women, with the advantage of simultaneous repair of severe concurrent cystoceles.

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Background: Dysfunction of the heart cells is one of the main causes of heart failure or lack of properly heart function. In the present study, human placenta extract (PE) along with poly lactic co-glycolic acid (PLGA) and poly hydroxyl butyrate (PHB) were used to make bioactive scaffolds using electrospinning method.
Materials and methods: Electrospinning method was used to make PLGA-PHB and PLGA-PHB-PE nanofibers. Morphological evaluation of PLGA-PHB and PLGA-PHB-PE nanofibers was done using electron microscope. Degradability rate, water absorption capacity, protein and adhesion strength of the scaffolds were investigated. Mesenchymal cells were extracted from adipose tissue. In order to confirm stem cells, CD34, CD45, CD90 and CD105 markers were performed by flow cytometry. Also, the expression of MyoD and Troponin T genes was performed by RT-PCR.
Results: The degradability of PLGA-PHB-PE scaffold was higher compared to PLGA-PHB in different days. Also, water absorption, protein and adhesive strength were higher in PLGA-PHB-PE scaffold compared to PLGA-PHB (p<0.05). Gene expression of MyoD and Troponin T genes was higher in cells grown on PLGA-PHB-PE scaffold compared to PLGA-PHB (p<0.05).
Conclusion: According to the results, it can be concluded that the PLGA-PHB-PE scaffold has a high potential to promote the cardiac differentiation of MSCs and can be used in cardiac tissue engineering for heart muscle repair.