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Background: Fatty liver disease is a type of fat aggregation in the liver cells. The Portulaca oleracea plant has hypolipidemic property. The aim of this study was to evaluate efficacy of Portulaca oleracea supplementation with a combination training program on the levels of some blood factors and health indicators of obese females with non- alcoholic fatty liver disease.
Materials and methods: 40 obese women were randomly selected and divided into four groups, including training group (n=10), training + supplement group (n=10), placebo group (n=10), and supplement group (n=10). The plasma levels of cardiovascular risk factors and health factors were measured before and after the twelve week intervention. The paired samples t- test and ANOVA was used to analyze data.
Results: Portulaca oleracea supplementation with a combination training program significantly reduced cholesterol (P=0.001), triglycerides (P<0.0001), LDL (P<0.0001), fat percentage (P<0.0001), and waist to hip ratio (P<0.0001) and a significant increase in serum level of HDL (P<0.0001), Body fat percentage (P<0.0001), waist- to- hip ratio (P=0.03), and BMI (P=0.01) in exercise + supplement group, exercise group, and supplement group (P <0.05).
Conclusion: Portulaca oleracea supplementation with a combination training program can be effective in reducing some blood and health indicators in obese women with non-alcoholic fatty liver

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Background: Exercise can cause inflammation and neutrophil activity. Neutrophils contain the enzyme myeloperoxidase that its main function is to produce reactive oxygen species. On the other hand, physical activity can improve immune function and antioxidant activity. Therefore, the aim of the present study was to evaluate neutrophil activity, changes in myeloperoxidase levels and total antioxidant capacity of healthy middle-aged men participating in regular leisure time exercises and untrained subjects.
Materials and methods: Twenty trained (age 53.58± 2.94 years, BMI 25.47±1.6) and 17 untrained (age 54.17±2.83 years, BMI 27.83±1.12) subjects participated in this study. Subjects performed modified Bruce treadmill test as a model of progressive exercise training. Blood samples were taken before, immediately after and one hour after the end of the test.
Results: There was a significant difference in the neutrophil counts of the trained group and also between both groups. Furthermore, the results showed significant difference in myeloperoxidase levels in trained compared to untrained group. Significant changes in total antioxidant capacity were observed in both groups and the trained group demonstrated higher levels of total antioxidant capacity.
Conclusion: Participation in regular leisure time exercises can improve neutrophil function, reduce myeloperoxidase levels and increase the total antioxidant capacity of healthy middle-aged men and may potentially slowdown the immunosenescence process.