fa بررسی ارتباط دیابت و فشار خون بالای ریوی در بیماران مبتلا به بیماری مزمن تنفسی مراجعه کننده به بیمارستان بوعلی تهران ريه Pulmonary تحليلي/مقطعي/توصيفي Survey/Cross Sectional/Descriptive <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">سابقه و هدف</span></span><i><span lang="FA" style="font-size:12.0pt"><span style="font-family:Nazanin"><span style="font-weight:normal">:</span></span></span></i> <i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="font-weight:normal">هیپرگلیسمی بر مسیرها</span></span></span></i><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="font-weight:normal">ی </span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="font-weight:normal">دخیل بر فشار خون شریانی ریوی موثر</span></span></span></i><i> </i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="font-weight:normal">است. هدف از این مطالعه </span></span></span></i><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="font-weight:normal">بررسی ارتباط دیابت و فشار خون بالای ریوی در بیماران مبتلا به بیماری مزمن تنفسی مراجعه کننده به بیمارستان بوعلی تهران بود. </span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="font-weight:normal"></span></span></i></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt">روش بررسی</span></span></span><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal">:</span></span></span></span></i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal"> <i>در این مطالعه توصیفی تحلیلی 149 پرونده از بیماران مبتلا به بیماری مزمن تنفسی در بیمارستان بوعلی‌ تهران از تاریخ &nbsp;1395 تا 1401 بررسی شدند. اطلاعات از پرونده‌ها استخراج و در فرم جمع&shy;آوری اطلاعات ثبت شد</i>.</span></span></span></span><i>&nbsp; </i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.3pt"><span style="font-weight:normal"></span></span></span></i></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt">یافته</span></span></span><span lang="FA" style="font-size:14.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">&shy;</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt">ها:</span></span></span> <i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">اطلاعات 149 بیمار با میانگین سنی 6/8 </span></span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span cambria="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">&plusmn;</span></span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal"> 65 سال بررسی شد. فراوانی فشار خون ریوی بالا 8/14 درصد و دیابت تایپ 2 9/32 درصد بود. بین فشار خون ریوی بالا </span></span></span></span></i><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">و</span></span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal"> جنسیت (34/0=</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">)، مصرف سیگار (64/0=</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">)، نوع داروی دیابت (70/0 = </span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">)، سن (97/0=</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">)، </span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">FEV1/FVC</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal"> (17/0 =</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">) و </span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">BMI</span></span></span></i><i> </i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">(</span></span></span></span></i><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">06/0 =</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">)</span></span></span></span></i><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">،</span></span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal"> ارتباطی یافت نشد. بین فشار خون ریوی بالا و دیابت (001/0></span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">)، مدت ابتلا به دیابت (03/0=</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">)، </span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">HbA1c‌</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal"> (001/0></span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">) و </span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">FBS</span></span></span></i><i> </i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">(001/0></span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">p</span></span></span></i><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">) ارتباط معنی‌داری وجود داشت</span></span></span></span></i><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.2pt"><span style="font-weight:normal">.</span></span></span></span></i></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt">نتیجه</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal">&shy;</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt">گیری</span></span></span><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal">:</span></span></span></span></i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal"> <i>فراوانی دیابت در بیماران با بیماری مزمن تنفسی با فشار خون بالای ریوی بیشتر از بیماران بدون فشار خون بالای ریوی است. </i></span></span></span></span><i><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal">مطالعات بیشتر در مورد تاثیر دیابت و هورمون‌های درگیر در کنترل قند خون بیماری با بیماری‌های مزمن تنفسی مبتلا به دیابت مورد نیاز است</span></span></span></span></i><i><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal">. </span></span></span></span></i><span lang="FA" style="font-size:12.0pt"><span b="" koodak="" style="font-family:"><span style="letter-spacing:-.3pt"><span style="font-weight:normal"></span></span></span></span></span></span></span></span></span></span><br> <br> <br> &nbsp; <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:11.0pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt">Background</span></b><span style="font-size:11.0pt">: Hyperglycemia affects pathways involved in pulmonary arterial blood pressure. The aim of this study was to investigate the association between diabetes and pulmonary hypertension in patients with chronic respiratory disease referred to Bu Ali Hospital in Tehran. </span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:11.0pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt">Materials and methods</span></b><span style="font-size:11.0pt">: In this descriptive-analytical study, 149 cases of patients with chronic respiratory disease in Tehran&#39;s Bu Ali Hospital from 1395 to 1401 were examined. Information was extracted from the files and recorded in the data collection form. </span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="line-height:11.0pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt">Results</span></b><span style="font-size:11.0pt">: The data of 149 patients with mean age of 65 &plusmn; 8.6 years were analyzed. The prevalence of pulmonary hypertension and type 2 diabetes were 14.8% and 32.9%, respectively. No relationship between pulmonary hypertension and gender (p=0.34), smoking (p=0.64), type of diabetes medicine (p=0.70), age (p=0.97), FEV1/FVC (17 p = 0.05) and BMI (p = 0.06) was found. There was a significant relationship between pulmonary hypertension and diabetes (p<0.001), duration of diabetes (p=0.03), HbA1c (p<0.001) and FBS (p<0.001).</span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:11.0pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt">Conclusion</span></b><span style="font-size:11.0pt">: The prevalence of diabetes in patients with chronic respiratory disease with pulmonary hypertension is higher than in patients without pulmonary hypertension. More studies are needed to evaluate the impact of diabetes and hormones involved in blood sugar control in patients with chronic respiratory diseases with diabetes. </span></span></span></span></span></span><br> &nbsp; دیابت, فشار خون ریوی, بیماری مزمن تنفسی, قند خون, هموگلوبین گلیکوزیله. Diabetes, Pulmonary hypertension, Chronic respiratory disease, Blood sugar, Glycosylated hemoglobin. 411 419 http://tmuj.iautmu.ac.ir/browse.php?a_code=A-10-1793-1&slc_lang=fa&sid=1 Basim Nikta بسیم نیکتا basimnikta@gmail.com 100319475328460012878 0009-0006-3503-2522 No Internal Medicine Resident, Department of Internal Medicine, Faculty of Medicine, Tehran Medical Sciences, Azad University, Tehran, Iran دستیار تخصصی گروه داخلی، دانشکده پزشکی، علوم پزشکی تهران، دانشگاه آزاد اسلامی، تهران، ایران , Zahra Shariati زهرا شریعتی shariatisima872@gmail.com 100319475328460012879 009-008-7425-3285 Yes Internal Medicine Specialist, Department of Internal Medicine, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran متخصص بیماری های داخلی، گروه بیماری‌های داخلی، دانشکده پزشکی، علوم پزشکی تهران، دانشگاه آزاداسلامی، تهران، ایران Shima MosalaNejad شیما مصلی نژاد shimaamosalanejad@gmail.com 100319475328460012880 100319475328460012880 No Internal Medicine Specialist, Department of Internal Medicine, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran متخصص بیماری های داخلی، گروه بیماری‌های داخلی، دانشکده پزشکی، علوم پزشکی تهران، دانشگاه آزاداسلامی، تهران، ایران Mehdi Afkar مهدی افکار mehdiafkar@gmail.com 100319475328460012881 100319475328460012881 No Community Medicine Specialist, Department of Community Medicine, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran متخصص پزشکی اجتماعی، دانشکده پزشکی، علوم پزشکی تهران، دانشگاه آزاد اسلامی، تهران، ایران Nazanin Biazar نازنین بی آزار nazanin.biazar@gmail.com 100319475328460012882 0009-0006-8042-3768 No Internal Medicine Resident, Department of Internal Medicine, Faculty of Medicine, Tehran Medical Sciences, Azad University, Tehran, Iran دستیار تخصصی گروه داخلی، دانشکده پزشکی، علوم پزشکی تهران، دانشگاه آزاد اسلامی، تهران، ایران