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:: Volume 30, Issue 2 (summer 2020) ::
MEDICAL SCIENCES 2020, 30(2): 174-184 Back to browse issues page
Safety and efficacy of antimicrobial nanostructured textiles: comparison with 11070 national standard
Afrah Sepehr1 , Sepideh Arbabi-Bidgoli 2, Seyyed Reza Hosseini Doost3
1- MSc, Pharmaceutical Sciences Research Center, Tehran Medical Sciences, Islamic Azad University (IAUTMU), Tehran, Iran
2- Professor, Department of Toxicology, Faculty of Pharmacy, Tehran Medical Sciences, Islamic Azad University (IAUTMU), Tehran, Iran , s.arbabi@iautmu.ac.ir
3- Professor, Department of Toxicology, Faculty of Pharmacy, Tehran Medical Sciences, Islamic Azad University (IAUTMU), Tehran, Iran
Abstract:   (2080 Views)
Background: This study aimed to evaluate the efficacy and safety of five randomly selected nanostructured products by the National Standard of No. 11070.
Materials and methods: Antibacterial activities of five different nanostructured textiles were assessed on specific microorganisms to human skin and environment. The physicochemical properties were determined by FTIR spectrum and the dermal toxicity was assessed by skin and eye irritation and corrosion test (OECD 404,405).
Results: Each of the 5 samples at concentrations of 0, 0.5, 1, 1.5, 2 and 5% had strong antibacterial activity compared to control treatments. Mild and reversible irritations were observed at all three concentrations of nanosilver (5, 50, and 500 ppm) after 24 hours exposing to yarn and tissue samples on female rabbits, and the FTIR test related to 5 products showed no change in group, before and after the treatments e.g. washing and contact with the test animals (rabbits). Tissues containing nano-silver particles had no irritating effect and eye lesions in rabbits.
Conclusion: According to the results, in addition to complying with the properties mentioned in the health license, the nanostructured textiles complied with the standard features of 11070.
Keywords: Nanostructured textiles, Skin, irritation, Corrosion, Effects, Antimicrobial effects.
Full-Text [PDF 442 kb]   (844 Downloads)    
Semi-pilot: Survey/Cross Sectional/Descriptive | Subject: Nanobiotechnology
Received: 2019/04/13 | Accepted: 2019/09/17 | Published: 2020/06/28
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Sepehr A, Arbabi-Bidgoli S, Hosseini Doost S R. Safety and efficacy of antimicrobial nanostructured textiles: comparison with 11070 national standard. MEDICAL SCIENCES 2020; 30 (2) :174-184
URL: http://tmuj.iautmu.ac.ir/article-1-1775-en.html


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Volume 30, Issue 2 (summer 2020) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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