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:: Volume 19, Issue 1 (Spring 2009) ::
MEDICAL SCIENCES 2009, 19(1): 11-15 Back to browse issues page
Effect of L-carnitine supplement on semen parameters in men with idiopathic infertility
Maryam Eidi 1, Omid Pouyan , Pooneh Shahmohammadi , Hojjatollah Saeidi , Masih Bahar , Akram Eidi
1- , maryameidi@gmail.com
Abstract:   (25338 Views)
Background: It is proposed that L-carnitine is a useful agent for treatment of various dysfunctions of sperm in infertile men. So, in the present study, effect of L-carnitine supplement on sperm parameters in men with idiopathic infertility was evaluated.
Materials and methods: Thirty infertile men, aged between 20 and 40 years, with the following baseline sperm selection criteria, including sperm count< 66.6×106, motility< 30%, viability< 60%, normal morphology< 35%, were studied. Patients received 3 gram per day L-carnitine for six months. Semen analysis was performed according to World Health Organization guidelines before study, and 3 and 6 months of therapy. Sperm parameters included liquefaction, pH, volume, sperm count, motility, viability and normal morphology.
Results: The results showed that L-carnitine supplementation increased significantly sperm count, motility, viability and normal morphogy and pregnancy rate after 3 months (p<0.01) and 6 months (p<0.001). Also, L-carnitine supplementation increased sperm motility and viability in idiophatic infertile men after 3 and 6 months (p<0.001). Five couples became pregnant during the study.
Conclusion: The present study indicated that L-carnitine supplementation is an appropriate drug in the treatment of men with idiopathic infertility.
Keywords: L-Carnitine, Sperm parameters, Idiopathic infertility, Men
Full-Text [PDF 140 kb]   (3979 Downloads)    
Subject: Epidemiology
Received: 2006/09/6 | Published: 2009/04/15
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Eidi M, Pouyan O, Shahmohammadi P, Saeidi H, Bahar M, Eidi A. Effect of L-carnitine supplement on semen parameters in men with idiopathic infertility. MEDICAL SCIENCES 2009; 19 (1) :11-15
URL: http://tmuj.iautmu.ac.ir/article-1-181-en.html


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Volume 19, Issue 1 (Spring 2009) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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