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Efficacy of intra-cuff dexamethasone and magnesium sulphate on frequency and severity of post- intubation sore throat
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Ladan Ansari1   , Kaveh Roostaeeian2 , Katayun Ansari3 , Gholamreza Asgari4 |
1- Department of Anesthesiology, Boo-Ali Hospital, Islamic Azad university, Tehran Medical Branch, Tehran, Iran , ladanansari46@gmail.com
2- Department of Anesthesiology, Boo-Ali Hospital, Islamic Azad university, Tehran Medical Branch, Tehran, Iran
3- Otorhinolaryngologist, Tehran University of Medical Sciences, Tehran, Iran
4- Homeopathic Physician, Shahid Beheshti University, Tehran, Iran |
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Abstract: (16710 Views) |
Background: Sore throat is a common problem after general anesthesia. This study compared the efficacy of intra-cuff dexamethasone, Magnesium Sulfate and placebo on sore throat.
Materials and methods: This was a randomized double blind clinical trial among 90 patients who underwent general anesthesia with tracheal intubation in Boo-Ali hospital in 2008. They were randomly assigned to receive either 16 mg of intra-cuff dexamethasone, or 50 milligram per kilogram of intra-cuff magnesium sulfate or intra-cuff air. The patients were evaluated after recovery, at the end of the day, and on the morning after surgery for sore throat and its severity, according to VAS. Statistic analysis was done by ANOVA and Chi-square tests.
Results: There was no significant difference between the incidence of sore throat after recovery, at the end of operation day, and on the morning after operation between three groups (P > 0.05), but there was significant reduction in sore throat severity in intra-cuff dexamethasone group on the day after operation (P < 0.05).
Conclusion: Using intra-cuff dexamethasone or intra-cuff magnesium sulfate are not effective methods in decreasing incidence of post intubation sore throat, but using intra-cuff dexamethaone decreases sore throat severity. |
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| Keywords: Tracheal intubation, Sore throat, Dexamethasone, Magnesium sulfate |
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Full-Text [PDF 359 kb]
(3062 Downloads)
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Semi-pilot: Controlled/Randomized clinical trial |
Subject:
Anesthesiology
Received: 2012/04/3 | Published: 2012/04/15
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