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MEDICAL SCIENCES 2022, 32(4): 368-378 Back to browse issues page
The effect of residual acetamiprid and dichlorvos in greenhouse cucumber on liver function and testicular germ cells on laboratory mice
Hamid Salehi Mishani1 , Alireza Jalalizand 2, Mehrdad Modaresi3
1- Department of Plant protection, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
2- Department of Animal Science, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran , arjalalizand@gmail.com
3- Department of Animal Science, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
Abstract:   (351 Views)
Background: Pesticides are widely used around the world, especially in underdeveloped and developing countries. However, the effect of residual amounts of these compounds on the physiological processes of the body has always been discussed.
Materials and methods: In this experimental study, 27cucumber plants were sprayed with a concentration equal to twofold recommended dose (acetamiprid (50 g/l) and dichlorvos (4 ml/l)). After 24 hours, the residual amount was obtained and to evaluate the effect of these residues, 20 mice were divided into 4 groups. The control group and groups 1, 2 and 3 that received dichlorvos,  acetamiprid, and combination of two pesticides respectively in drinking water.
Results: The residual pesticide in cucumber was obtained for acetamiprid 1.5 mg/kg and for dichlorvos 0.5 mg/kg. Their effect indicated a significant decrease in body weight and blood albumin levels (p<0.01) and an increase in liver enzymes (aspartate transaminase and alanine transaminase) and had changes in the number of testicular germ cells (p<0.05).
Conclusion: Liver disorders and reduced reproductive potential in male mice can be attributed to the addition of pesticides to their drinking water. Monitoring programs to evaluate the presence of residual pesticides in food should be done continuously and special attention should be paid to the management of consumption of these pesticides.
Keywords: Crops, Chemical pesticides, Liver, Germ cells, Laboratory mice
Full-Text [PDF 380 kb]   (234 Downloads)    
Semi-pilot: Experimental | Subject: Animal Biology
Received: 2022/05/22 | Accepted: 2022/08/28 | Published: 2022/12/31
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Salehi Mishani H, Jalalizand A, Modaresi M. The effect of residual acetamiprid and dichlorvos in greenhouse cucumber on liver function and testicular germ cells on laboratory mice. MEDICAL SCIENCES 2022; 32 (4) :368-378
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Volume 32, Issue 4 (winter 2022) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
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