1. 1. Prince DA, Connors BW. Mechanisms of interictal epileptogenesis. Adv Neurol 1986;44:275-99. 2. Loscher W, Klitgaard H, Twyman RE, Schmidt D. New avenues for anti-epileptic drug discovery and development. Nat Rev Drug Discov 2013;12:757-76. [ DOI:10.1038/nrd4126] 3. Jefferys JG. Advances in understanding basic mechanisms of epilepsy and seizures. Seizure 2010;19:638-46. [ DOI:10.1016/j.seizure.2010.10.026] 4. Katzung B, Trevor A, Editors. Basic and clinical pharmacology. 13th ed. USA: McGraw-Hill Education; 2014. P.1216. 5. Mazarati AM, Liu H, Soomets U, Sankar R, Shin D, Katsumori H, et al. Galanin modulation of seizures and seizure modulation of hippocampal galanin in animal models of status epilepticus. J Neurosci 1998;18:10070-7. [ DOI:10.1523/JNEUROSCI.18-23-10070.1998] 6. de Lanerolle NC, Kim JH, Robbins RJ, Spencer DD. Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res 1989;495:387-95. [ DOI:10.1016/0006-8993(89)90234-5] 7. Liu H, Mazarati AM, Katsumori H, Sankar R, Wasterlain CG. Substance P is expressed in hippocampal principal neurons during status epilepticus and plays a critical role in the maintenance of status epilepticus. Proc Natl Acad Sci U S A 1999;96:5286-91. [ DOI:10.1073/pnas.96.9.5286] 8. Marrosu F, Mereu G, Fratta W, Carcangiu P, Camarri F, Gessa GL. Different epileptogenic activities of murine and ovine corticotropin-releasing factor. Brain Res 1987;408:394-8. [ DOI:10.1016/0006-8993(87)90413-6] 9. Tallent MK, Siggins GR. Somatostatin depresses excitatory but not inhibitory neurotransmission in rat CA1 hippocampus. J Nneurophysiol 1997;78:3008-18. [ DOI:10.1152/jn.1997.78.6.3008] 10. Bausch SB, Esteb TM, Terman GW, Chavkin C. Administered and endogenously released kappa opioids decrease pilocarpine-induced seizures and seizure-induced histopathology. J Pharmacol Exp Ther 1998;284:1147-55. 11. Civelli O, Zhou Q, Editors. Orphan G protein-coupled receptors and novel neuropeptides. 1st ed. Switzerland: Springers; 2008. [ DOI:10.1007/978-3-540-78351-0] 12. Naydenova E, Todorov P. Nociceptin/orphanin (N/OFQ) analogues: Chemistry and biology. J Univ Chem Technol Metallurgy 2011; 2011:334. 13. Donica CL, Awwad HO, Thakker DR, Standifer KM. Cellular mechanisms of nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor regulation and heterologous regulation by N/OFQ. Mol Pharmacol 2013;83:907-18. [ DOI:10.1124/mol.112.084632] 14. Gavioli EC, Duarte FS, Guerrini R, Calo G, Rae GA, TC MDL. GABA(A) signalling is involved in N/OFQ anxiolytic-like effects but not in nocistatin anxiogenic-like action as evaluated in the mouse elevated plus maze. Peptides 2008;29:1404-12. [ DOI:10.1016/j.peptides.2008.04.004] 15. Witkin JM, Statnick MA, Rorick-Kehn LM, Pintar JE, Ansonoff M, Chen Y, et al. The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence. Pharmacol therap 2014;141:283-99. [ DOI:10.1016/j.pharmthera.2013.10.011] 16. Tajalli S, Jonaidi H, Abbasnejad M, Denbow DM. Interaction between nociceptin/orphanin FQ (N/OFQ) and GABA in response to feeding. Physiol Behav 2006;89:410-3. [ DOI:10.1016/j.physbeh.2006.07.009] 17. Aparicio LC, Candeletti S, Binaschi A, Mazzuferi M, Mantovani S, Di Benedetto M, et al. Kainate seizures increase nociceptin/orphanin FQ release in the rat hippocampus and thalamus: a microdialysis study. J Neurochem 2004;91:30-7. [ DOI:10.1111/j.1471-4159.2004.02633.x] 18. Bregola G, Zucchini S, Rodi D, Binaschi A, D'Addario C, Landuzzi D, et al. Involvement of the neuropeptide nociceptin/orphanin FQ in kainate seizures. J Neurosci 2002;22:10030-8. [ DOI:10.1523/JNEUROSCI.22-22-10030.2002] 19. Calo G, Guerrini R, Rizzi A, Salvadori S, Regoli D. Pharmacology of nociceptin and its receptor: a novel therapeutic target. Br J Pharmacol 2000;129:1261-83. [ DOI:10.1038/sj.bjp.0703219] 20. Feng Y, Chao DM, Li WM, Cao YX, Wang YQ, Wu GC. Inhibition of nociceptin/orphanin FQ on penicillin-induced seizures in rats. Brain Res 2004;1020:214-9. [ DOI:10.1016/j.brainres.2004.05.116] 21. Rubaj A, Zgodzinski W, Gustaw K, Sieklucka-Dziuba M. Nociceptin, OP4 receptor ligand in different models of experimental epilepsy. Peptides 2002;23:497-505. [ DOI:10.1016/S0196-9781(01)00636-2] 22. Binaschi A, Zucchini S, Bregola G, Rodi D, Mazzuferi M, Reinscheid RK, et al. Delayed epileptogenesis in nociceptin/orphanin FQ-deficient mice. Neuroreport 2003;14:825-7. [ DOI:10.1097/00001756-200305060-00009] 23. Baluchnejadmojarad T, Roghani M. Coenzyme q10 ameliorates neurodegeneration, mossy fiber sprouting, and oxidative stress in intrahippocampal kainate model of temporal lobe epilepsy in rat. J Mol Neurosci 2013;49:194-201. [ DOI:10.1007/s12031-012-9886-2] 24. Shen H, Liu L, Huo Z, Lin Z. Hippocampal stem cell grafting-mediated recovery of injured hippocampus in the rat model of temporal lobe epilepsy. Int J Neurosci 2010;120:647-54. [ DOI:10.3109/00207454.2010.509526] 25. Liao ZJ, Liang RS, Shi SS, Wang CH, Yang WZ. Effect of baicalin on hippocampal damage in kainic acid-induced epileptic mice. Exp Ther Med 2016;12:1405-11. [ DOI:10.3892/etm.2016.3461] 26. Hu K, Li SY, Xiao B, Bi FF, Lu XQ, Wu XM. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta Neurol Belg 2011;111:205-12. 27. Sakoori K, Murphy NP. Reduced degeneration of dopaminergic terminals and accentuated astrocyte activation by high dose methamphetamine administration in nociceptin receptor knock out mice. Neurosci Lett 2010;469:309-13. [ DOI:10.1016/j.neulet.2009.12.014] 28. Jauregui-Huerta F, Ruvalcaba-Delgadillo Y, Gonzalez-Castaneda R, Garcia-Estrada J, Gonzalez-Perez O, Luquin S. Responses of glial cells to stress and glucocorticoids. Curr Immunol Rev 2010;6:195-204. [ DOI:10.2174/157339510791823790] 29. Leggett JD, Harbuz MS, Jessop DS, Fulford AJ. The nociceptin receptor antagonist [Nphe1,Arg14,Lys15]nociceptin/orphanin FQ-NH2 blocks the stimulatory effects of nociceptin/orphanin FQ on the HPA axis in rats. Neuroscience 2006;141:2051-7. [ DOI:10.1016/j.neuroscience.2006.05.036] 30. Guo H, Zhao L, Zhang BH, Li J, Chen X. Apoptosis of K562 cells induced by nociceptin/orphanin FQ. Zhongguo shi yan xue ye xue za zhi. 2006;14:1116-9. [In Chinese] 31. Bregola G, Candeletti S, Romualdi P, Simonato M. Limbic seizures increase pronociceptin mRNA levels in the thalamic reticular nucleus. Neuroreport 1999;10:541-6. [ DOI:10.1097/00001756-199902250-00018] 32. Tallent MK, Madamba SG, Siggins GR. Nociceptin reduces epileptiform events in CA3 hippocampus via presynaptic and postsynaptic mechanisms. J Neurosci 2001;21:6940-8. [ DOI:10.1523/JNEUROSCI.21-17-06940.2001] 33. Armagan G, Bojnik E, Turunc E, Kanit L, Gunduz Cinar O, Benyhe S, et al. Kainic acid-induced changes in the opioid/nociceptin system and the stress/toxicity pathways in the rat hippocampus. Neurochem Int 2012;60:555-64. [ DOI:10.1016/j.neuint.2012.02.015] 34. Racine RJ. Modification of seizure activity by electrical stimulation. I. After-discharge threshold. Clin Neurophysiol 1972;32:269-79. [ DOI:10.1016/0013-4694(72)90176-9] 35. Nicol B, Lambert DG, Rowbotham DJ, Okuda-Ashitaka E, Ito S, Smart D, et al. Nocistatin reverses nociceptin inhibition of glutamate release from rat brain slices. Eur J Pharmacol 1998;356::R1-3. [ DOI:10.1016/S0014-2999(98)00545-7] 36. Jalili C, Salahshoor MR, Moradi S, Pourmotabbed A, Motaghi M. The therapeutic effect of the aqueous extract of boswellia serrata on the learning deficit in kindled rats. Int J Prev Med 2014;5:563-8. 37. Chauviere L, Rafrafi N, Thinus-Blanc C, Bartolomei F, Esclapez M, Bernard C. Early deficits in spatial memory and theta rhythm in experimental temporal lobe epilepsy. J Neurosci 2009;29:5402-10. [ DOI:10.1523/JNEUROSCI.4699-08.2009] 38. Miltiadous P, Stamatakis A, Koutsoudaki PN, Tiniakos DG, Stylianopoulou F. IGF-I ameliorates hippocampal neurodegeneration and protects against cognitive deficits in an animal model of temporal lobe epilepsy. Exp Nneurol 2011;231:223-35. [ DOI:10.1016/j.expneurol.2011.06.014] 39. Duarte JM, Agostinho PM, Carvalho RA, Cunha RA. Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ mice. PloS One 2012;7:e21899. [ DOI:10.1371/journal.pone.0021899] 40. Tourandokht Baluchnejadmojarad, Roghani M, Kamran M, Karimi N. The Effect of Alpha-Lipoic Acid on Learning and Memory Deficit in a Rat Model of Temporal Lobe Epilepsy. Basic Clin Neurosci 2012; 3: 58-66 41. Shapiro LA, Wang L, Ribak CE. Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats. Epilepsia 2008;49:33-41. [ DOI:10.1111/j.1528-1167.2008.01491.x] 42. Mansouri Z, Sabetkasaei M, Moradi F, Masoudnia F, Ataie A. Curcumin has neuroprotection effect on homocysteine rat model of Parkinson. J Mol Neurosci 2012;47:234-42. [ DOI:10.1007/s12031-012-9727-3] 43. Roozendaal B, Lengvilas R, McGaugh JL, Civelli O, Reinscheid RK. Orphanin FQ/nociceptin interacts with the basolateral amygdala noradrenergic system in memory consolidation. Learn Mem 2007;14:29-35. [ DOI:10.1101/lm.403607] 44. Sandin J, Georgieva J, Schott PA, Ogren SO, Terenius L. Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats. Eur J Neurosci 1997;9:194-7. [ DOI:10.1111/j.1460-9568.1997.tb01367.x] 45. Palotai M, Adamik A, Telegdy G. Involvement of neurotransmitters in the action of the nociceptin/orphanin FQ peptide-receptor system on passive avoidance learning in rats. Neurochem Res 2014;39:1477-83. [ DOI:10.1007/s11064-014-1337-8] 46. Mallimo EM, Kusnecov AW. The role of orphanin FQ/nociceptin in neuroplasticity: relationship to stress, anxiety and neuroinflammation. Front Cell Neurosci 2013;7:173. [ DOI:10.3389/fncel.2013.00173] 47. Sandin J, Ogren SO, Terenius L. Nociceptin/orphanin FQ modulates spatial learning via ORL-1 receptors in the dorsal hippocampus of the rat. Brain Res 2004;997:222-33. [ DOI:10.1016/j.brainres.2003.11.008] 48. Nabeshima T, Noda Y, Mamiya T. The role of nociceptin in cognition. Brain Res 1999;848:167-73. [ DOI:10.1016/S0006-8993(99)01906-X] 49. Hiramatsu M, Inoue K. Effects of nocistatin on nociceptin-induced impairment of learning and memory in mice. Eur J Pharmacol 1999;367:151-5. [ DOI:10.1016/S0014-2999(99)00003-5]
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