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A review of the mechanism of action of cyanobacteria to control diabetes and blood sugar
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Sina Zaliani1    , Bahareh Nowruzi2 |
1- Master's student, Department of Biotechnology, Faculty of Converging Sciences and Technologies, Islamic Azad University, Science and Research Branch, Tehran, Iran
2- Associate Professor, Department of Biology, SR.C., Islamic Azad University, Tehran, Iran , bahareh.nowruzi@srbiau.ac.ir |
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Abstract: (25 Views) |
Bioactive compounds in cyanobacteria are full of various nutrients and chemical compounds, including proteins, carbohydrates, fats, vitamins, minerals, pigments, chlorophyll and enzymes. Spirulina, a genus of cyanobacteria, is full of active molecules and nutrients that have numerous pharmacological activities and applications, including antioxidants, anti-inflammatory, immunotherapy, immune booster, anti-cancer, antiviral activity, and neuroprotective properties. It is also used as a dietary supplement for weight loss and blood glucose levels in mouse models and type 2 diabetics. Various mechanisms, including anti-inflammatory activity, increased insulin sensitivity, gluconeogenesis inhibition, antioxidant activity, modulation of the composition of the intestinal microbiota, improvement of glucose homeostasis and activation of the insulin receptor, were attributed to this unique behavior of spirulina. In this review article, by studying the latest available articles, it provides all the essential information about the efficacy and possible side effects of identified bioactive compounds derived from cyanobacteria. However, further studies are still needed to fully explain its effects on human physiology and determine the optimal dose of treatment.
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| Keywords: Cyanobacteria, Diabetes, Blood sugar control, Spirulina |
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Full-Text [PDF 1233 kb]
(19 Downloads)
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Semi-pilot: Review |
Subject:
biotechnology
Received: 2024/09/8 | Accepted: 2024/12/8 | Published: 2025/09/1
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