[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Webmail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
:: Volume 20, Issue 2 (Summer 2010) ::
MEDICAL SCIENCES 2010, 20(2): 83-89 Back to browse issues page
Effect of vibration stress on the sexually dimorphic nucleus (SDN) of hypothalamus of immature male Wistar rat
Parichehr Yaghmaei 1, Kazem Parivar , Homa Mohseni Kouchesfahani , Afshin Pirnia
Abstract:   (27145 Views)
Background: The sexually dimorphic nuclei in the preoptic area (SDN-POA) of hypothalamus are a cluster of cells which size, shape and their cellular morphology are related to gender and age. Different stressors affect on hypothalamus nuclei. In this study, effect of vibration stress was studied on endocrine system and sexually dimorphic nucleus (SDN) of hypothalamus.
Materials and methods: In this experimental study, male immature Wistar rats (15 days old) were divided into 3 groups Control, Experimental E350 and E500. Experimental groups were exposed to vibration stress by shaker with frequency 350mot/min and 500mot/min, 15 minutes daily for 3 weeks. At the end of this period, serum plasmic hormones, such as cortisol, testosterone, estradiol and progesterone, were evaluated. Sections of the brain tissue were prepared for histological and microscopic studies.
Results: Cortisol levels increased significantly in experimental E350 (p<0.05) and E500 (p<0.001) groups. Testosterone level decreased significantly in experimental E500 (p<0.01) group. Progesterone increased significantly in experimental E500 (p<0.01). Estradiol did not show a significant decrease. Microscopic studies of brain showed significant decrease of number and density of sexually dimorphic nuclei in the preoptic area (SDN-POA) of hypothalamus in male immature Wistar rats with vibration stress.
Conclusion: Vibration stress induces dysfunction of hypothalamus- pituitary- adrenal axis which can lead to homosexuality and other sexually behavioral disorders.
Keywords: Vibration stress, Sexually dimorphic nuclei, Rat.
Full-Text [PDF 2183 kb]   (5041 Downloads)    
Subject: Epidemiology
Received: 2010/09/2 | Published: 2010/09/15
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Parichehr Yaghmaei, Kazem Parivar, Homa Mohseni Kouchesfahani, Afshin Pirnia. Effect of vibration stress on the sexually dimorphic nucleus (SDN) of hypothalamus of immature male Wistar rat. MEDICAL SCIENCES 2010; 20 (2) :83-89
URL: http://tmuj.iautmu.ac.ir/article-1-291-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 20, Issue 2 (Summer 2010) Back to browse issues page
فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch
Persian site map - English site map - Created in 0.05 seconds with 37 queries by YEKTAWEB 4645